Figure 2

The serum metabolome is indistinguishable between patients with and without weakness following AVF surgery. (A) Violin plots shown the change in grip strength (post-operative minus pre-operative) for patients classified as ‘normal’ and those with ‘weakness’. (B) Heatmaps showing the fold change in aqueous phase metabolites at baseline (pre-operative), 6 weeks post-operatively, and the change for patients classified as ‘normal’ and those with ‘weakness’. (C) Heatmaps showing the fold change in lipid phase metabolites at baseline (pre-operative), 6 weeks post-operatively, and the change for patients classified as ‘normal’ and those with ‘weakness’. (D) Correlation between the change in serum tryptophan levels and the change in grip strength. Comparisons between two groups were performed using an unpaired Student’s t-test. Metabolite comparisons were performed using an unpaired Student’s t-test. with FDR correction for multiple comparisons.