Figure 4

Decreased amino acid levels are found in ARHD patients with sensory disability. (A) Violin plots showing changes in monofilament and sensory nerve conduction tests in patients classified as having mild sensory disability and those without (normal). (B) Heatmaps showing the fold change in aqueous phase metabolites at baseline (pre-operative), 6 weeks post-operatively, and the change for patients classified as ‘normal’ and those with ‘sensory disability’. (C) Heatmaps showing the fold change in lipid phase metabolites at baseline (pre-operative), 6 weeks post-operatively, and the change for patients classified as ‘normal’ and those with ‘sensory disability’. Comparisons between two groups were performed using an unpaired Student’s t-test. Metabolite comparisons were performed using an unpaired Student’s t-test. with FDR correction for multiple comparisons.