Figure 4 | Scientific Reports

Figure 4

From: Allosteric modulation of the fish taste receptor type 1 (T1R) family by the extracellular chloride ion

Figure 4

Site X does not affect the susceptibility of T1Rs to Cl−. Dose‒response curves of stable cell lines expressing (A) hT1R2/hT1R3 T102E to sucralose, (B) mfT1R2a/mfT1R3 T105E to L-Gln, (C) mfT1R2b/mfT1R3 T105E to L-Ala, or (D) mfT1R2c/mfT1R3 T105E to L-Pro, with G16gust44. Data are shown as the mean ± SEM (n = 3–4 independent experiments performed in duplicate or triplicate). Cross marks in the graph represent EC50 values. VEH: responses against the buffer.

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