Table 2 Ventilatory and physiological variables at T0 and T1.

From: The effect of increased positive end expiratory pressure on brain tissue oxygenation and intracranial pressure in acute brain injury patients

 

T0

T1

P value

Vt (mL)

450 (400–478)

450 (390–470)

0.12

Pinsp (cmH2O)

8 (6–10)

8 (6–10)

0.86

PEEP (cmH2O)

6 (5–8)

10 (8–12)

0.001

RR (breaths per minute)

24 (19–28)

24 (18–28)

0.24

FiO2

0.50 (0.35–0.60)

0.50 (0.40–0.60)

0.78

MAP (mmHg)

104 (93–117)

104 (91–119)

0.64

ICP (mmHg)

12 (7–18)

12 (7–17)

0.42

CPP (mmHg)

91 (79–105)

91 (76–105)

0.47

PbtO2 (mmHg)

21 (16–29)

23 (18–30)

0.001

P/F

192 (141–273)

206 (143–284)

0.76

PaCO2 (mmHg)

40 (36–45)

41 (37–47)

0.52

  1. Data are expressed as median and interquartile range.
  2. Vt tidal volume, Pinsp inspiratory pressure, PEEP positive end expiratory pressure, RR respiratory rate, FiO2 inspired fraction of oxygen, MAP mean arterial pressure, ICP intracranial pressure, CPP cerebral perfusion pressure, PbtO2 brain tissue partial pressure of oxygen, P/F arterial partial pressure of oxygen/ inspired fraction of oxygen, PaCO2 arterial partial pressure of carbon dioxide.
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