Figure 5 | Scientific Reports

Figure 5

From: SARS-CoV-2 Spike protein peptides displayed in the Pyrococcus furiosus RAD system preserve epitopes antigenicity, immunogenicity, and virus-neutralizing activity of antibodies

Figure 5

Analysis of SAR-CoV-2 neutralising activity of anti-RAD-SCoV-epitope mouse sera. (A) Virus neutralization test (VNT) with the anti-RAD-SCoV-epitope sera. Samples were tested for neutralising antibodies using the cytopathic effect‐based virus neutralisation test (CPE‐VNT) using a SARS-CoV-2 (original Wuhan isolate). VERO CCL-81 cells with strong blue staining indicates uninfected cells. Panel (A) is a composite image from the original data, with samples ordered numerically. Original images are shown in Supplementary Figure S4. (B) Heatmap representation of the results for each antibody according to neutralization at indicated dilutions.

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