Table 2 Cox regression analysis of GNRI and ECW/ICW associated with overall survival.

From: Prognostic value of the combined effect of nutritional status and body water component in patients with colorectal cancer

 

Crude

Model A

Model B

Model C

HR (95%CI)

P

HR (95%CI)

P

HR (95%CI)

P

HR (95%CI)

P

GNRI

 ≥ 103.5

Ref

 

Ref

 

Ref

 

Ref

 

 < 103.5

1.455 (1.049–2.018)

0.025

1.441 (1.033–2.010)

0.032

1.448 (1.023–2.050)

0.037

1.762 (1.141–2.720)

0.011

ECW/ICW

 < 63.7%

Ref

 

Ref

 

Ref

 

Ref

 

 ≥ 63.7%

1.859 (1.366–2.528)

 < 0.001

1.895 (1.366–2.629)

 < 0.001

1.533 (1.093–2.150)

0.013

1.477 (1.030–2.118)

0.034

  1. Model A: adjusted for age and sex.
  2. Model B: adjusted for model A plus TNM stage, comorbidities, smoking and drinking history, family history, surgery, chemotherapy, radiotherapy, targeted therapy, immunotherapy and nutritional support.
  3. Model C: adjusted for model B plus PG-SGA, NRS2002, BMI, NLR, FM and FFM, with GNRI and ECW/ICW for mutual adjustment.
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