Figure 2 | Scientific Reports

Figure 2

From: Microglial CD300f immune receptor contributes to the maintenance of neuron viability in vitro and after a penetrating brain injury

Figure 2

CD300f inhibition induced neurotoxicity in vivo. (A) Bar graphs showing the percentage of lesion volume in rat cortex 72 h after being injected with saline (n = 3), rCD300f-IgG2a (n = 5, 30 μg/ml), or control IgG2a (n = 4, 30 μg/ml) and measured by Nissl staining. (B) Representative images of mouse Thy1-YFP-H cortex injected with saline or rCD300f-IgG2a and contralateral non-injected cortex (Scale bars 100 μM). (C) Bar graph showing the number of YFP + cortical neurons in Thy1-YFP-H cortex after intracortical injection of saline (n = 4), rCD300f-IgG2a (n = 7, 30 μg/ml), or control IgG2a (n = 6, 30 μg/ml) Data show mean ± SEM; p corresponds to one way ANOVA followed by Holm-Sidak´s test.

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