Figure 4

CD300f inhibition by rCD300f-Fc is specific. (A,B) Representative images of Nissl stained Sects. 72 h after WT or CD300f−/− animals were intracortically injected with IgG1 or rCD300f-IgG1 (Scale bar 200 μM). (C) Analysis of lesion volume was performed by Nissl staining 72 h after (WT injection of IgG1 n = 9, rCD300f-IgG1 n = 10, KO injection of IgG1 n = 10 and rCD300f-IgG1 n = 9). Two independent experiments were performed in different days including all treatments in each day. Data show mean ± SEM; p corresponds to one way ANOVA followed by Tukey’s test.