Figure 4
From: ESX1 gene as a potential candidate responsible for male infertility in nonobstructive azoospermia
Box-plot graphs of 52 selected genes analysed in TCam-2 cells with activated ESX1 gene and controls analysed by RNA-seq. The 33 out of the selected genes presented upregulation and 19 downregulation with a minimum of a twofold change (p < 0.05) in cells with activated ESX1 in comparison to both applied controls. WT wild type, NC negative control with nonspecific gRNAs for the human genome, ESX1 cells with the activated ESX1 gene using specific gRNAs for the ESX1 sequence. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.
