Table 3 The top 20 genes significantly up-regulated in HR-NB vs. LIR-NB.
No | Gene | Description | Fold Change | P value |
|---|---|---|---|---|
1 | H4C3 | H4 clustered histone 3 | 30.916 | 3.43E−08 |
2 | THRSP | Thyroid hormone responsive | 25.793 | 1.70E−09 |
3 | TRARG1 | Trafficking regulator of GLUT4 (SLC2A4) 1 | 21.326 | 3.84E−06 |
4 | CYP21A2 | Cytochrome P450 family 21 Subfamily A member 2 | 20.358 | 7.25E−10 |
5 | CIDEC | Cell death inducing DFFA like effector c | 18.992 | 6.04E−07 |
6 | DES | Desmin | 18.251 | 5.47E−12 |
7 | DPT | Dermatopontin | 18.023 | 6.90E−12 |
8 | S100A12 | S100 calcium binding protein A12 | 17.576 | 2.00E−11 |
9 | H1-4 | H1.4 linker histone, cluster member | 17.292 | 1.23E−07 |
10 | DLK1 | Delta like non-canonical Notch ligand 1 | 16.116 | 2.76E−10 |
11 | MRAP | Melanocortin 2 receptor accessory protein | 15.255 | 4.62E−07 |
12 | PLIN1 | Perilipin 1 | 15.235 | 2.36E−08 |
13 | NTS | Neurotensin | 15.205 | 3.23E−08 |
14 | GPD1 | Glycerol-3-phosphate dehydrogenase 1 | 14.816 | 7.06E−10 |
15 | FABP4 | Fatty acid binding protein 4 | 14.238 | 3.53E−10 |
16 | SFRP2 | Secreted frizzled related protein 2 | 13.779 | 3.78E−09 |
17 | PRG2 | Proteoglycan 2, pro eosinophil major basic protein | 13.389 | 1.36E−10 |
18 | FAM166B | Family with sequence Similarity 166 member B | 11.802 | 2.98E−09 |
19 | HBB | Hemoglobin subunit beta | 10.902 | 2.01E−11 |
20 | MGST1 | Microsomal glutathione S-transferase 1 | 10.654 | 4.85E−08 |