Table 4 The top 20 genes significantly down-regulated in HR-NB vs. LIR-NB.
No | Gene | Description | Fold change | P value |
|---|---|---|---|---|
1 | TMEM163 | Transmembrane protein 163 | 0.281 | 2.66E−06 |
2 | UNC5D | unc-5 netrin receptor D | 0.281 | 0.000631 |
3 | VWDE | von Willebrand factor D and EGF domains | 0.280 | 0.000974 |
4 | ZCCHC12 | Zinc finger CCHC-type containing 12 | 0.270 | 0.000174 |
5 | SLC5A7 | Solute carrier family 5 member 7 | 0.263 | 0.001530 |
6 | GRIN3A | glutamate ionotropic receptor NMDA type subunit 3A | 0.263 | 0.000867 |
7 | TPBGL | Trophoblast glycoprotein like | 0.254 | 2.42E−08 |
8 | GFAP | Glial fibrillary acidic protein | 0.250 | 0.002749 |
9 | SST | somatostatin | 0.249 | 0.001242 |
10 | CDH10 | Cadherin 10 | 0.236 | 0.000629 |
11 | HTR1B | 5-Hydroxytryptamine receptor 1B | 0.222 | 0.000863 |
12 | SPHKAP | SPHK1 interactor, AKAP domain containing | 0.220 | 5.53E−05 |
13 | LRRTM3 | Leucine rich repeat Transmembrane neuronal 3 | 0.193 | 7.60E−05 |
14 | UPP2 | Uridine phosphorylase 2 | 0.193 | 6.05E−08 |
15 | UTS2 | Urotensin 2 | 0.168 | 3.07E−05 |
16 | DPP10 | Dipeptidyl peptidase like 10 | 0.128 | 6.47E−06 |
17 | UCN3 | Urocortin 3 | 0.118 | 3.34E−07 |
18 | ADCYAP1 | Adenylate cyclase activating Polypeptide 1 | 0.112 | 1.04E−06 |
19 | GRP | Gastrin releasing peptide | 0.084 | 5.88E−06 |
20 | CGA | Glycoprotein hormones, Alpha polypeptide | 0.062 | 4.93E−09 |