Figure 4 | Scientific Reports

Figure 4

From: Phenotypic and molecular characterization of novel pulmonary adenocarcinoma cell lines established from a dog

Figure 4

Sensitivity to vinorelbine in the canine PAC cell lines. (a) CPACd cell lines and (b) CPACr cell lines were treated with vinorelbine (0–10,000 nM) for 48 h. Cell proliferation was measured using cell counting kit-8. Data are represented as the percentage of control (0 nM; mean ± SD). Results are representative of three independent experiments. (c) The IC50 are calculated in each cell line. Results are represented as the mean ± SD of three independent experiments. *P < 0.05, **P < 0.01: The IC50 is significantly higher than the parent cell lines; † P < 0.05, †† P < 0.01: The IC50 is significantly lower than that of the parent cell lines.

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