Table 2 Genotype frequencies and percentages for the sample cohort, total LS cohort and divided by country.
From: MTHFR C677T and A1298C polymorphism’s effect on risk of colorectal cancer in Lynch syndrome
MTHFR SNP | Combined sample cohort total n (%) | Australia total n (%) | Poland total n (%) | Norway total n (%) | Germany total n (%) | Spain total n (%) |
|---|---|---|---|---|---|---|
A1298C (rs1801131) | ||||||
AA | 1,251 (48) | 272 (47) | 186 (47) | 104 (54) | 235 (42) | 454 (52) |
AC | 1,122 (43) | 259 (45) | 173 (44) | 72 (38) | 246 (44) | 372 (43) |
CC | 220 (8.5) | 50 (8.6) | 35 (8.9) | 16 (8.3) | 73 (13) | 46 (5.3) |
Total | 2,593 (100) | 581 (100) | 394 (100) | 192 (100) | 554 (100) | 872 (100) |
C677T (rs1801133) | ||||||
CC | 1,037 (40) | 245 (43) | 178 (46) | 85 (45) | 234 (42) | 295 (34) |
CT | 1,231 (48) | 274 (48) | 172 (44) | 83 (43) | 254 (46) | 448 (51) |
TT | 314 (12) | 54 (9.4) | 41 (10) | 23 (12) | 66 (12) | 130 (15) |
Total | 2,582 (100) | 573 (100) | 391 (100) | 191 (100) | 554 (100) | 873 (100) |
