Table 4 The Dice’s and Simpson’s coefficients of AE signals were detected between amphetamine and each MAO-B inhibitor.
Coefficients | Amfetamine | Selegiline | Rasagiline | Safinamide | |
|---|---|---|---|---|---|
Total signals | 1530 | 585 | 672 | 254 | |
All signals | Da | Ref. | 0.18 | 0.23 | 0.12 |
Sb | Ref. | 0.33 | 0.37 | 0.43 | |
Top 50% in odds ratio | D | Ref. | 0.10 | 0.11 | 0.05 |
S | Ref. | 0.11 | 0.11 | 0.10 | |
Top 25% in odds ratio | D | Ref. | 0.05 | 0.06 | 0.03 |
S | Ref. | 0.07 | 0.08 | 0.04 | |
Top 10% in odds ratio | D | Ref. | 0.02 | 0.02 | 0.00 |
S | Ref. | 0.05 | 0.05 | 0.01 | |
PTs included in SOCs (psychiatric, neurological, cardiac, and vascular disorders) | D | Ref. | 0.36 | 0.43 | 0.22 |
S | Ref. | 0.48 | 0.54 | 0.60 | |
PTs included in SOCs (psychiatric, neurological) | D | Ref. | 0.40 | 0.47 | 0.23 |
S | Ref. | 0.58 | 0.59 | 0.61 |
