Figure 5
Infection extinction versus establishment. The distribution for the frequency (black dots) or complementary cumulative frequency (solid red curve), or \(1-\)(cumulative frequency), of the number of cells consumed by the infection, \(N_\text {cells}-T(\infty )\), out of \(N_\text {cells} = {4 \times 10^4}\,{\text {cells}}\), based on \(10^6\) SM simulations. For the frequency distribution, each black dot represents the fraction of the SM simulations where exactly this discrete number of cells were consumed by the infection (e.g. 0, 1, 2, ...). The \(95^{\textrm{th}}\)-percentile upper and lower bounds (95% bounds) for the number of cells consumed by extinct infections is between zero and the vertical (grey) dotted line, and that by established infections is indicated by a pair of vertical (orange) dashed lines flanking the median (vertical solid line). Parameters are the same as in Fig. 4 for an antiviral reducing the virus production rate, \(p\rightarrow (1-\varepsilon )p\), at efficacy \(\varepsilon =0.79\) such that \(T^{*}/N_\text {cells} = 0.5\) (see Methods).
