Table 3 Metabolites associated with orthostatic blood pressure responses in fully adjusted models.
From: The relationships between the plasma metabolome and orthostatic blood pressure responses
Chemical name | Super pathway | Sub-pathway | β coff. | 95% CI | P value | ||
|---|---|---|---|---|---|---|---|
Lower limit | Upper limit | ||||||
1 | Behenoyl Dihydrosphingomyelin | Lipid | Dihydrosphingomyelins | − 0.70 | − 1.26 | − 0.37 | 3.42 × 10–5 |
2 | Sphingomyelin | Lipid | Dihydrosphingomyelins | − 0.60 | − 0.93 | − 0.27 | 3.58 × 10–4 |
3 | Sphingosine | Lipid | Sphingosines | − 0.54 | − 0.86 | − 0.21 | 1.28 × 10–3 |
4 | Sphingadienine | Lipid | Sphingosines | − 0.50 | − 0.83 | − 0.18 | 2.27 × 10–3 |
5 | Dihomo-Linoleoylcarnitine | Lipid | Fatty acid metabolism (Acyl Carnitine, polyunsaturated) | 0.53 | 0.20 | 0.86 | 1.84 × 10–3 |
6 | 1-Myristoyl-2-Arachidonoyl-GPC | Lipid | Phosphatidylcholine (PC) | − 0.53 | − 0.86 | − 0.20 | 1.57 × 10–3 |
7 | Creatine | Amino acid | Creatine metabolism | − 0.59 | − 0.94 | − 0.24 | 1.04 × 10–3 |
8 | Glutamine | Amino acid | Glutamate metabolism | 0.53 | 0.20 | 0.86 | 1.72 × 10–3 |
9 | Glutamine degradant | Partially characterized molecule | Partially characterized molecules | 0.66 | 0.26 | 1.05 | 1.08 × 10–3 |
10 | Cysteine s-sulfate | Amino acid | Methionine, Cysteine, SAM and Taurine metabolism | − 0.55 | − 0.88 | − 0.22 | 1.24 × 10–3 |
11 | Gucuronide of Piperine metabolite | Xenobiotic | Food component/plant | − 0.58 | − 0.92 | − 0.24 | 7.24 × 10–4 |
