Table 2 Comparison of the characteristics of patients requiring neurocritical care by 10 acute neurocritical disorders.

From: Epidemiology and disease burden of patients requiring neurocritical care: a Brazilian multicentre cohort study

Variables

NPO (n = 317)

TBI (n = 218)

IS (n = 211)

ENC (n = 155)

Seizures (n = 91)

ICH (n = 77)

SAH (n = 70)

SNI (n = 25)

SCI (n = 19)

NMD (n = 11)

p value

Age (years), mean ± SD

53.4 ± 14.7

54.3 ± 22.1

69.3 ± 16.9

65.7 ± 20.2

58.7 ± 22.7

62 ± 15.3

57.6 ± 14.2

55.7 ± 17.6

36.5 ± 18.5

50 ± 20.8

 < 0.001a

Male sex, n (%)

131 (41.3)

162 (74.3)

107 (50.7)

72 (46.5)

46 (50.5)

37 (48.1)

22 (31.4)

19 (76)

14 (73.7)

8 (72.7)

 < 0.001b

GCS, median (IQR)

15 (14–15)

9 (3–14)

14 (12–15)

13 (9–14)

14 (11–15)

10 (4–14)

10 (3–14)

10 (4–14)

15 (15—15)

15 (14—15)

 < 0.001c

APACHE II at ICU admission, median (IQR)

7 (4–10)

14 (10–21)

11 (7–16)

15 (10–25)

10 (6–15)

15 (9–19)

14 (8–20)

20 (12–24)

7 (3–12)

7 (5–10)

 < 0.001c

SAPS III at ICU admissiond, median (IQR)

31 (24–39)

47 (38–57)

52 (42–58)

57 (47–68)

41 (33–54)

54.5 (44–65.5)

48 (40–60)

59 (44.5–65.5)

35 (27–43)

42 (36–49)

 < 0.001c

SOFA at ICU admissione, median (IQR)

1 (0–3)

5 (2–8)

2 (0–4)

4 (2–8)

2 (0–4)

5; 4 (2–7)

4 (2–8)

6 (1.5–9)

3 (1–4)

0 (0–2)

 < 0.001c

Number of Hs at ICU admission, n (%)

 Zero

162 (51.1)

64 (29.4)

109 (51.7)

47 (30.3)

44 (48.4)

30 (39)

24 (34.3)

6 (24)

8 (42.1)

6 (54.5)

 < 0.001b

 One

96 (30.3)

51 (23.4)

55 (26.1)

39 (25.2)

24 (26.4)

20 (26)

20 (28.6)

5 (20)

5 (26.3)

3 (27.3)

 Two

41 (12.9)

49 (22.5)

30 (14.2)

32 (20.6)

14 (15.4)

13 (16.9)

14 (20)

4 (16)

5 (26.3)

1 (9.1)

 Three or more

18 (5.7)

54 (24.8)

17 (8.1)

37 (23.9)

9 (9.9)

14 (18.2)

12 (17.1)

10 (40)

1 (5.3)

1 (9.1)

Invasive MV, n (%)

53 (16.7)

139 (63.8)

55 (26.1)

65 (41.9)

24 (26.4)

50 (64.9)

45 (64.3)

14 (56)

12 (63.2)

3 (27.3)

 < 0.001b

Tracheostomy, n (%)g

7 (13.2)

43 (30.9)

18 (32.7)

22 (33.8)

5 (20.8)

23 (46)

15 (33.3)

4 (28.6)

7 (58.3)

2 (66.7)

0.016b

Length of ICU stay until 30th day, median (IQR)

3 (2–5)

11 (4–29)

4 (3–11)

6 (3–17.5)

4 (2–9)

16 (6–30)

11.5 (4–22)

13 (4–26)

30 (7.5–30)

4 (3–30)

 < 0.001b

30-day mortality, n (%)

7 (2.2)

56 (25.7)

24 (11.4)

41 (26.5)

4 (4.4)

22 (28.6)

24 (34.3)

9 (36)

1 (5.3)

0 (0)

 < 0.001b

mRS on ICU outcome or until 30th dayf, n (%)

 0

121 (38.3)

40 (18.3)

50 (24)

18 (11.6)

36 (40.4)

2 (2.6)

7 (10)

4 (16)

1 (5.3)

4 (36.4)

 < 0.001b

 1

75 (23.7)

30 (13.8)

37 (17.8)

16 (10.3)

16 (18)

11 (14.5)

6 (8.6)

4 (16)

4 (21.1)

2 (18.2)

 2

50 (15.8)

16 (7.3)

17 (8.2)

16 (10.3)

7 (7.9)

8 (10.5)

6 (8.6)

0 (0)

0 (0)

1 (9.1)

 3

29 (9.2)

15 (6.9)

22 (10.6)

16 (10.3)

5 (5.6)

3 (3.9)

7 (10)

1 (4)

2 (10.5)

0 (0)

 4

26 (8.2)

31 (14.2)

34 (16.3)

24 (15.5)

10 (11.2)

13 (17.1)

7 (10)

3 (12)

4 (21.1)

2 (18.2)

 5

8 (2.5)

30 (13.8)

24 (11.5)

24 (15.5)

11 (12.4)

17 (22.4)

13 (18.6)

4 (16)

7 (36.8)

2 (18.2)

 6

7 (2.2)

56 (25.7)

24 (11.5)

41 (26.5)

4 (4.5)

22 (28.9)

24 (34.3)

9 (36)

1 (5.3)

0 (0)

Unfavourable outcome (mRS score 4, 5, or 6)f, n (%)

41 (13)

117 (53.7)

82 (39.4)

89 (57.4)

25 (28.1)

52 (68.4)

44 (62.9)

16 (64)

12 (63.2)

4 (36.4)

 < 0.001b

  1. APACHE II acute physiology and chronic health evaluation, ENC encephalopathy, GCS Glasgow Coma Scale, ICH intracerebral haemorrhage, IQR interquartile range, IS ischaemic stroke, mRS modified Rankin Scale, MV mechanical ventilation, n absolute frequency, NMD neuromuscular disease, NPO postoperative care of elective neurosurgery, SAH subarachnoid haemorrhage, SAPS III simplified acute physiology score III, SCI spinal cord injury, SD standard deviation, SNI central nervous system infection, SOFA sequential organ failure assessment, TBI traumatic brain injury, % percentage within column.
  2. aSignificance of the one-way analysis of variance (ANOVA).
  3. bSignificance of the chi-square test.
  4. cSignificance of the Kruskal–Wallis test.
  5. dMissing data on SAPS III: 3 for NPO, 7 for TBI, 10 for STR, 1 for ENC, 1 for seizures, 5 for ICH, 5 for SAH, 1 for SNI and 2 for SCI.
  6. eMissing data on SOFA: 6 for NPO, 9 for TBI, 15 for IS, 6 for seizures, 7 for ICH, 6 for SAH, 1 for SNI and 4 for SCI.
  7. fMissing data on mRS and unfavourable outcome: 1 for NPO, 3 for IS, 2 for seizures, 1 for ICH.
  8. gPercentage of patients placed on invasive mechanical ventilation.
Back to article page