Table 3 Unadjusted odds ratios of prognostic factors for mortality and unfavourable outcome among patients requiring neurocritical care.

From: Epidemiology and disease burden of patients requiring neurocritical care: a Brazilian multicentre cohort study

Factors (n total = 1194)

ICU dischargea

Death on ICUa

Unadjusted OR (95% CI) for ICU mortalityb

p valuec

Favourable outcome (mRS score 1, 2, or 3)a

Unfavourable outcome (mRS score 4, 5, or 6)a

Unadjusted OR (95% CI) for unfavourable outcomeb

p valuec

Age (years)

(n = 1006) 58.5 ± 19

(n = 188) 60.9 ± 21.1

1.006 (0.998–1.014)

0.122

(n = 705) 57.7 ± 18.7

(n = 482) 60.4 ± 20.2

1.007 (1.001–1.013)

0.017

Sex

 Female

519/576 (87)

75/576 (13.0)

Ref

 

360/572 (62,9)

212/572 (37.1)

Ref

 

 Male

505/618 (81.7)

113/618 (18.3)

1.494 (1.088–2.052)

0.013

345/615 (56.1)

270/615 (43.9)

1.329 (1.053–1.677)

0.017

GCS

(n = 1006) 14 (11–15)

(n = 188) 7 (3–13)

0.812 (0.784–0.840)

 < 0.001

(n = 705) 15 (14–15)

(n = 482) 10 (3–14)

0.764 (0.738–0.792)

 < 0.001

APACHE II

(n = 1006) 10 (6–15)

(n = 188) 21.5 (15–27.5)

1.179 (1.151–1.207)

 < 0.001

(n = 705) 8 (5–12)

(n = 482)17 (12–23)

1.195 (1.168–1.222)

 < 0.001

SAPS III

(n = 984) 42 (32–54)

(n = 175) 60 (47–73)

1.066 (1.054–1.078)

 < 0.001

(n = 692) 39 (29–49)

(n = 460) 56 (44–67)

1.075 (1.065–1.086)

 < 0.001

SOFA

(n = 968) 2 (1–4)

(n = 172) 8 (5–10)

1.366 (1.302–1.433)

 < 0.001

(n = 679) 1 (0–3)

(n = 454) 6 (3–9)

1.434 (1.369–1.503)

 < 0.001

Number of Hs

 Zero

478/500 (95.6)

22/500 (4.4)

Ref

 

380/494 (76.9)

114/494 (23.1)

Ref

 

 One

283/318 (89)

35/318 (11)

2.687 (1.545–4.672)

 < 0.001

207/318 (65.1)

111/318 (34.9)

1.787 (1.309–2.44)

 < 0.001

 Two

154/203 (75.9)

49/203 (24.1)

6.91 (4.049–11.801)

 < 0.001

82/202 (40.6)

120/202 (59.4)

4.878 (3.437–6.924)

 < 0.001

 Three or more

91/173 (52.6)

82/173 (47.4)

19.578 (11.625–32.972)

 < 0.001

36/173 (20.8)

137/173 (79.2)

12.685 (8.313–19.356)

 < 0.001

Coverage of hospitalization costs

 Private insurance

552/603 (91.5)

51/603 (8.5)

Ref

 

432/596 (72.5)

164/596 (27.5)

Ref

 

 Public insurance

454/591 (76.8)

137/591 (23.2)

3.266 (2.313–4.610)

 < 0.001

273/591 (46.2)

318/591 (53.8)

3.068 (2.409–3.908)

 < 0.001

Type of admission

 Elective

310/317 (97.8)

7/317 (2.2)

Ref

 

275/316 (87.0)

41/316 (13.0)

Ref

 

 Emergency

696/877 (77.4)

181/877 (22.6)

11.517 (5.350–24.793)

 < 0.001

430/871 (49.4)

441/871 (50.6)

6.879 (4.828–9.801)

 < 0.001

  1. APACHE II acute physiology and chronic health evaluation II, GCS Glasgow Coma Scale, Number of Hs number of secondary injuries (resulting from the sum of the presence of hypotension, hypoxemia, hyperthermia, hypercapnia, hypocapnia, hypoglycaemia, hyponatremia, hypothermia, intracranial hypertension, and clinical evidence of herniation), Ref. reference category, SAPS III simplified acute physiology score III, SOFA sequential organ failure assessment.
  2. aCategorical variables (sex, number of Hs, coverage of hospitalization costs, type of admission, and number of deaths) are described as absolute frequencies/total number of cases in the row (percentages), and quantitative variables are described as (number of valid cases) mean and standard deviation (age) or median and interquartile range (all other variables).
  3. bOdds ratio (OR) and 95% confidence interval (95% IC) of the univariate binary logistic regression model.
  4. cWald test p value, results < 0.05 indicate statistical significance.
Back to article page