Figure 12

Changes in the chemical shift of a tryptophan residue (HN: 10.294, N = 130.890) upon titration with the three substrates cellopentaose (Glc5), cellohexaose (Glc6), and xyloglucan tetradecamer (XG14). Panel A: Overlay of 15N-HSQC spectra recorded when ScLPMO9A was titrated with 0.05, 0.1, and 1.0 mM cellopentaose. Panel B: Overlay of 15N-HSQC spectra recorded when ScLPMO9A was titrated with 0.1, 0.5, and 2.6 mM cellohexaose. Panel C: Overlay of 15N-HSQC spectra recorded when ScLPMO9A was titrated with 0.4, 2.0, and 8.0 mM XG14. Arrows indicate the direction of the change in chemical shift in all three panels.