Table 5 Post-surgical malignancy rate of FNAB and FNAB with BRAFV600E genetic testing in different cytology Bethesda groups.

From: BRAFV600E genetic testing should be recommended for Bethesda III or V thyroid nodules based on fine-needle aspiration

Bethesda groups

FNAB alone

FNAB with BRAFV600E genetic testing

p

Number of surgical nodules

Number of malignant nodules

Malignancy rate

Number of surgical nodules

Number of malignant nodules

Malignancy rate

 

I

16

8

50.00%

12

9

75.00%

0.253

II

68

19

27.94%

17

6

35.29%

0.563

III

63

32

50.79%

85

78

91.76%

 < 0.001

IV

33

9

27.27%

10

1

10.00%

0.407

V

194

175

90.21%

152

150

98.68%

0.001

VI

1691

1680

99.35%

1729

1725

99.77%

0.073

Total

2065

1923

93.12%

2005

1969

98.20%

 < 0.001