Table 5 Genetic correlations of binary falls against variables of interest.
From: The genetics of falling susceptibility and identification of causal risk factors
Variable 1 | Variable 2 | rg* | p-Value | Source |
|---|---|---|---|---|
Combined falls | HES falls | 0.858 | 2.19E−27 | Internal GWAS |
Combined falls | GP falls | 0.995 | 1.37E−51 | Internal GWAS |
HES falls | GP falls | 0.748 | 6.75E−06 | Internal GWAS |
Combined falls | Published binary falls | 0.701 | 7.42E−17 | Trajanoska et al.13 |
HES falls | Published binary falls | 0.694 | 2.87E−11 | Trajanoska et al.13 |
GP falls | Published binary falls | 0.691 | 1.64E−18 | Trajanoska et al.13 |
Physical characteristics | ||||
BMI | Combined falls | 0.3511 | 1.17E−11 | Yengo et al.63 |
WHR | Combined falls | 0.3674 | 1.93E−11 | Internal GWAS |
Hand grip max | Combined falls | − 0.205 | 3.17E−05 | Internal GWAS |
Mental health | ||||
Depression | Combined falls | 0.4144 | 1.41E−11 | Howard et al.64 |
Anxiety | Combined falls | 0.5374 | 0.007 | Otowa et al.65 |
Neuroticism | Combined falls | 0.3199 | 3.19E−09 | Internal GWAS |
Social/behavioural | ||||
Physical activity | Combined falls | − 0.166 | 0.012 | Internal GWAS |
Education years | Combined falls | − 0.288 | 8.42E−08 | Internal GWAS |
Alzheimer’s | Combined falls | − 0.036 | 0.63 | Internal GWAS |
Townsend deprivation index | Combined falls | 0.4136 | 4.78E−08 | Internal GWAS |
Alcohol consumption | Combined falls | 0.1325 | 0.21 | Internal GWAS |
Cigarettes per day | Combined falls | 0.0092 | 3.11E−07 | Internal GWAS |
