Table 7 The penalty points of the proposed chromatographic method according to the Analytical Eco-scale.

From: White targeted chromatographic screening method of Molnupiravir and its metabolite with degradation kinetics characterization and in-silico toxicity

Reagents/Instruments

Penalty points (PPs)

Acetonitrile

3

NaOH

2

HCl

4

H2O2

4

Energy of HPLC

0

Occupational hazard

0

waste

3

PPs

16

Eco-scale score

84

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