Table 9 Comparison of whiteness evaluation of the proposed HPLC–DAD method together with reported methods using RGB12 model.

From: White targeted chromatographic screening method of Molnupiravir and its metabolite with degradation kinetics characterization and in-silico toxicity

Method number

Method name

R (%)

G (%)

B (%)

Whiteness (%)

1

Proposed HPLC–DAD

97.5

88.8

92.5

92.9

2

Reported HPLC-DAD9

92.5

90.0

92.5

91.7

3

Reported micellar HPLC-DAD11

95.0

93.8

88.8

92.5

4

Reported biological HPLC–MS/MS13

110.0

82.5

85.0

92.5

5

Reported HPTLC-DAD12

90.0

80.0

91.9

87.3

6

Reported spectrophotometry11

82.5

100.0

90.4

91.0

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