Figure 7
From: Disrupted brain mitochondrial morphology after in vivo hydrogen sulfide exposure
Quantitative comparison of a range of mitochondrial morphometric outcomes obtained after acute H2S exposure. Top panel. Example of mitochondrial images with disrupted morphology after acute H2S exposure. Representative images were selected to show the breadth of disrupted mitochondrial morphology assessed in this study. Full details are provided in the main text. Bottom panel. Each data point represents the individual value of a mitochondrion within each condition. Box and whisker plots were used to visualize the spread of data points under each condition. Each box (interquartile distance) encloses 50% of the data, with the median value of the variable displayed as a line. The top and bottom of the box mark the limits of the ± 25% of the variable population (i.e., upper and lower quartiles). The lines extending from the top and bottom of the box (whiskers) mark the minimum and maximum values within the dataset that fall within an acceptable range. Any value outside this range, called an outlier, is displayed as an individual point. Mitochondrion morphology score (A) spanning from 1(worst) to 5 (best). (B–F) The percentage of mitochondria with a particular feature under each condition [abnormal mitochondrial matrix (B), increased roundness (C), abnormal cristae (D), increased lamination (E), and abnormal outer mitochondrial membrane (F)]. ANOVA tests were run for each parameter, followed by Tukey's post-hoc. Equal letters mean no statistical differences.
