Table 2 Comparison of the scores of DT and CT groups at baseline, 3 weeks and 6 weeks.

From: Rapid improvements and subsequent effects in major depressive disorder patients with somatic pain using rTMS combined with sertraline

  

DT group

CT group

Time effect

Group effect

Time x group effect

HAMD

Baseline

31.6 ± 8.3

32.4 ± 8.1

164.12***

2.857

9.614***

3 weeks

25.9 ± 7.6

22.6 ± 8.6

6 weeks

21.3 ± 7.9

15.4 ± 7.2

HAMA

Baseline

24.1 ± 7.3

23.3 ± 6.4

159.372***

14.024***

25.297***

3 weeks

19.7 ± 6.5

11.0 ± 7.8

6 weeks

14.1 ± 6.4

8.1 ± 6.9

NRS

Baseline

7.0 ± 1.4

6.9 ± 1.3

187.496***

15.961

11.597***

3 weeks

5.5 ± 1.4

3.8 ± 1.6

6 weeks

3.9 ± 1.4

2.6 ± 1.2

MMN latency

Baseline

221.2 ± 27.1

224.8 ± 28.2

8.143***

1.298

2.299

3 weeks

215.9 ± 20.0

209.6 ± 20.1

6 weeks

214.6 ± 21.2

203.3 ± 18.6

P300 latency

Baseline

394.8 ± 27.2

392.2 ± 28.5

22.05***

2.194

2.289

3 weeks

386.1 ± 21.0

379.6 ± 19.1

6 weeks

385.0 ± 22.2

372.8 ± 16.6

P300 amplitude

Baseline

2.7 ± 2.2

2.5 ± 3.5

16.477***

1.697

11.249***

3 weeks

2.8 ± 2.8

3.2 ± 2.6

6 weeks

3.0 ± 3.2

5.3 ± 3.3

  1. HAMD Hamilton Rating Scale for Depression, HAMA Hamilton Rating Scale for Anxiety, NRS Numerical Rating Scales, MMN mismatch negativity, DT the drug therapy group, CT the drug and rTMS combined therapy group.
Back to article page