Table 1 Descriptive statistics of selected parameters for ATL and SED.

From: Regular exercise delays microvascular endothelial dysfunction by regulating antioxidant capacity and cellular metabolism

Parameter

Athletes (mean ± SD)

Sedentary (mean ± SD)

p value

Age (years)

52.39 ± 15.31

51.40 ± 14.83

 > 0.05

BMI (Kg/m2)

22.19 ± 1.21

23.09 ± 1.55

 > 0.05

VO2 max (ml/Kg/min)

58 ± 7

43 ± 6

 < 0.01

NOx (mM)

50.35 ± 18.97 **

38.99 ± 15.27

 < 0.01

HBF basal (pu)

206.33 ± 34.93

189.59 ± 37.65

 > 0.05

HBF heating (pu)

332.04 ± 36.36 ***

270.50 ± 35.36

 < 0.001

HBF ischemia (pu)

374.42 ± 38.43 ***

277.64 ± 42.16

 < 0.001

FBF basal (pu)

206.78 ± 34.39

184.50 ± 36.26

 > 0.05

FBF heating (pu)

225.08 ± 43.27 ***

179.45 ± 38.73

 < 0.001

FBF ischemia (pu)

378.46 ± 37.74 ***

269.23 ± 40.86

 < 0.001

SIRT1 (ng/ml, plasma)

4.05 ± 0.613 ***

2.84 ± 0.80

 < 0.001

miR29

4.25 ± 0.73 ***

3.07 ± 0.65

 < 0.001

PGC-1α mRNA

2.73 ± 0.70 ***

1.89 ± 0.65

 < 0.001

TOSC vs. peroxyl radicals

18.74 ± 2.62 ***

12.01 ± 1.91

 < 0.001

TOSC vs. hydroxyl radicals

9.86 ± 1.50 ***

6.04 ± 1.50

 < 0.001

  1. The data are expressed as mean ± SD. Statistical analysis was performed by unpaired t-tests: **p < 0.01, ***p < 0.001 (ATL vs. SED). BMI body mass index; VO2 Max maximal oxygen consumption, NOx nitric oxide, HBF hand blood flow, FBF foot blood flow, IRT1 Sirtuin 1, PGC-1α PPAR-γ co-activator-1 α, TOSC total oxyradical scavenging capacity.