Figure 1
Inflammasome-dependent Pathways. According to the Pearson correlation score, components belonging to the inflammasome complex were significantly (FDR p < 0.001) correlated with the POP group (prolapse, pessary, and postoperative). The association was calculated using the observation_metadata_correlation.py script on rarefied otu_table.biom (5000 reads/sample). The levels of IFN-γ, IL-1β, IL-4, IL-10, IL-12p70, and TNF-α varied among groups. Comparisons were performed using one-way analysis of variance. When a significant p value was observed (p less than 0.05), a multiple comparison test was used to determine which groups were different. Data are shown as the mean value ± standard error of the mean (SEM). Pearson’s scores for each bacterial species are shown in parentheses. FDR, false discovery rate. **p < 0.05, ***p < 0.001.
