Figure 3 | Scientific Reports

Figure 3

From: Purine metabolism-related genes and immunization in thyroid eye disease were validated using bioinformatics and machine learning

Figure 3

For PMGs, GO, and KEGG analyses were performed. (a): The GO circle illustrates the scatter map of the selected gene's logFC. (b): The KEGG barplot and bubble illustrates the scatter map of the logFC of the indicated gene. Through GO enrichment analysis, we identified an ensemble of 351 core target genes that are intricately implicated across an array of BP, MF, and CC. This comprehensive gene set offers a profound insight into the multidimensional landscape of cellular functionality. Building upon this, KEGG enrichment analysis further demarcated the principal signaling pathways. Remarkably, we discovered that the over-expressed genes predominantly converge upon metabolic pathways.

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