Figure 4 | Scientific Reports

Figure 4

From: Purine metabolism-related genes and immunization in thyroid eye disease were validated using bioinformatics and machine learning

Figure 4

The development of the PMGs signature. (a): Regression of the 10 TED-related genes using LASSO, It can be seen that these 10 genes are significantly related to TED and PMGs. (b): Cross-validation is used in the LASSO regression to fine-tune parameter selection, Cross-validation indicated that the results obtained by the proposed algorithm were stable. (c-d): Accuracy and error of this model, These results suggest that the stability of this study is good. (e): Venn, The intersection core genes of lasso and SVM-RFE were 10. (f): AUC of 10 hub genes. (g): AUC of train group.

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