Figure 7

Hsa_circRNA_001676 deficiency reduced tumor growth of CRC in vivo by regulating miR-556-3p/G3BP2 axis. (A) Photographs of xenograft tumors. (B) Curves of tumor volumes. (C) TUNEL staining analysis of cell apoptosis in tumor tissues (Scale bar = 100 μm). RT-qPCR analysis of (D) hsa_circRNA_001676, (E) miR-556-3p and (F) G3BP2 levels in tumor tissues. (G) H&E (upper panel) stained histological images of the tumor tissues. IHC (lower panel) analysis of G3BP2 protein expression in tumor tissues (Scale bar = 100 μm). *P < 0.05; ***P < 0.001.