Figure 9

Radius of gyration of anti-miRNAs and siRNAs during MD simulation. (A) has-miR-146a-5p, (B) has-miR-7155, (C) HIF1A siRNA, (D) TNFSF11 siRNA. Employing PEG-PEI as a carrier for has-miR-146a-5p and has-miR-7155-5p, PEG for HIF1A, and PEI for TNFSF11 resulted in the formation of more compact polymer-RNA complexes.