Table 5 The average of results among RNAis and different type of carriers.

From: In silico engineering and simulation of RNA interferences nanoplatforms for osteoporosis treating and bone healing promoting

Carrier

has-miR-146a-5p

has-miR-7155-5p

HIF1A

TNFSF11

PEG

PEI

PEG-PEI

PEG

PEI

PEG-PEI

PEG

PEI

PEG-PEI

PEG

PEI

PEG-PEI

vdW

−163.27

−37.82

−130.99

−41.62

−255.16

−123.55

−152.37

−60.23

−25.3

−10.79

−102.79

−92.22

Electrostatic energy

−44.97

17.07

−241.85

−37.18

−154.97

0.14

−27.79

−47.02

−21.07

−5.1

−180.03

−62.29

Total energy

−208.25

−20.75

−372.84

−78.8

−410.13

−123.41

−180.16

−107.24

−46.37

−15.9

−282.82

−154.5

SASA

97.1941

92.29

91.0163

92.41

82.3212

85.5460

41.9838

45.6116

45.0956

43.2122

40.7477

43.9826

Gyration radius

2.4297

2.1736

2.1084

2.7556

2.4739

2.9489

1.6069

2.1073

2.1339

2.2696

1.7092

2.0530

RMSD

2.6534

2.2128

1.9522

3.1690

2.6966

2.9361

1.2511

1.7515

1.7996

2.2100

1.2948

1.6635