Table 3 Cox multivariable analysis of relative risk of death from pancreatic ductal adenocarcinoma.
From: The possible dual role of Ang-2 in the prognosis of pancreatic cancer
Multivariable—Ang-2 tumor expression | ||
|---|---|---|
Hazard ratio (95% CI) | p value | |
Age (years) | 1.00 (0.98–1.03) | 0.91 |
Sex (male) | 0.97 (0.63–1.50) | 0.89 |
Stage IA–IIA | 1.00 | |
Stage IIB | 2.23 (1.23–4.04) | 0.008 |
Stage III–IV | 3.74 (1.96–7.15) | < 0.001 |
Adjuvant treatment (yes) | 0.71 (0.47–1.08) | 0.11 |
Radical surgery (R0) | 0.57 (0.34–0.95) | 0.03 |
Ang-2 epithelial expression (high) | 0.49 (0.31–0.78) | 0.003 |
logCA19-9 | 1.27 (0.99–1.63) | 0.06 |
logCRP | 1.48 (1.02–2.14) | 0.04 |
logCEA | 1.33 (0.64–2.77) | 0.44 |
Multivariable—Ang-2 serum expression | ||
|---|---|---|
Hazard ratio (95% CI) | p value | |
Age | 1.01 (0.99–1.03) | 0.40 |
Sex (male) | 1.02 (0.74–1.31) | 0.91 |
Stage IA–IIA | 1.00 | |
Stage IIB | 1.96 (1.29–2.96) | 0.001 |
Stage III–IV | 2.75 (2.05–5.04) | < 0.001 |
Adjuvant therapy administered | 0.63 (0.45–0.88) | 0.006 |
Radical surgery | 0.71 (0.48–1.06) | 0.09 |
Serum Ang-2 (high) | 1.48 (1.08–2.04) | 0.02 |
