Table 3 Univariate and multivariate analysis of TyG index and LVEF < 40%.

From: The relationship between insulin resistance, serum alkaline phosphatase, and left ventricular dysfunction following myocardial infarction

Variable

Univariate analysis

Multivariate analysis

OR (95%CI)

P value

OR (95%CI)

P value

Age

1.026 (1.004–1.049)

0.020

1.012 (0.986–1.038)

0.376

Male

1.371 (0.812–2.317)

0.238

  

SBP

0.979 (0.968–0.991)

0.001

0.983 (0.970–0.996)

0.012

DBP

0.985 (0.967–1.003)

0.104

  

RHR

1.020 (1.007–1.034)

0.002

1.014 (1.000–1.029)

0.055

Ischemic time

1.000 (0.999–1.003)

0.734

  

WBC

1.014 (0.982–1.046)

0.401

  

Hb

0.984 (0.973–0.995)

0.005

0.992 (0.979–1.005)

0.248

TyG

1.019 (0.695–1.494)

0.924

  

FBG

1.084 (1.026–1.146)

0.004

1.016 (0.937–1.102)

0.702

TG

0.598 (0.410–0.873)

0.008

0.652 (0.429–0.992)

0.046

BUN

1.240 (1.144–1.343)

 < 0.001

1.127 (0.996–1.275)

0.058

Creatinine

1.018 (1.009–1.027)

 < 0.001

1.002 (0.989–1.015)

0.790

LDL-C

1.018 (0.744–1.392)

0.911

  

HDL-C

1.765 (0.844–3.694)

0.131

  

TC

1.050 (0.840–1.313)

0.666

  

UA

1.002 (1.000–1.004)

0.012

1.000 (0.999–1.002)

0.651

ApoA1

1.597 (0.541–4.715)

0.396

  

ApoB

1.594 (0.608–4.181)

0.343

  

Lp(a)

1.000 (0.999–1.001)

0.954

  

LAD as IRA

2.677 (1.548–4.628)

 < 0.001

2.452 (1.352–4.449)

0.003

Extent of coronary artery disease

1-vessel

1

–

1

–

2-vessel

1.94 (0.903–4.167)

0.089

1.545 (0.686–3.481)

0.294

3-vessel

2.463 (1.209–5.018)

0.013

1.266 (0.540–2.969)

0.587

Gensini score

1.012 (1.007–1.017)

 < 0.001

1.009 (1.003–1.016)

0.003

Hypertension

0.814 (0.509–1.302)

0.390

  

Diabetes mellitus

1.875 (1.147–3.063)

0.012

0.919 (0.399–2.119)

0.843

Dyslipidemia

1.617 (0.988–2.648)

0.056

  

Current Smoking

1.326 (0.818–2.149)

0.253

  

Atrial fibrillation

1.074 (0.317–3.640)

0.909

  

Family history of CAD

1.339 (0.456–3.933)

0.595

  

Family history of cerebrovascular disease

1.941 (1.121–3.361)

0.018

1.378 (0.419–4.530)

0.598

Serum AP level Tertile

I (low)

1

–

1

–

II (middle)

1.529 (0.809–2.893)

0.191

1.857 (0.920–3.750)

0.084

III (high)

2.198 (1.197–4.036)

0.011

2.598 (1.331–5.071)

0.005

Antiplatelets

2.580 (0.930–7.153)

0.069

  

Beta-blocker

0.770 (0.178–3.330)

0.726

  

Calcium inhibitor

0.649 (0.349–1.207)

0.172

  

ACEI

–

0.998

  

Angiotensin II antagonist

0.712 (0.214–2.367)

0.580

  

Diuretic

2.263 (0.472–10.851)

0.307

  

Insulin

1.421 (0.537–3.760)

0.479

  

Oral antidiabetic drug

2.137 (1.173–3.892)

0.013

1.779 (0.722–4.387)

0.211

Statin

2.736 (0.981–7.632)

0.055

  

Atrial fibrillation

1.074 (0.317–3.640)

0.909

  

Ventricular Tachycardia

2.59 (0.529–12.692)

0.240

  

Heart arrest

3.026 (0.600–15.258)

0.180

  

Pulmonary Infection

2.189 (0.928–5.164)

0.074

  

Hydropericardium

1.795 (0.207–15.562)

0.596

  
  1. TyG triglyceride-glucose, TG/HDL-C ratio triglyceride/high-density lipoprotein cholesterol ratio, STEMI ST-elevation myocardial infarction, WBC white blood cell, ACEI angiotensin converting enzyme inhibitor, Hb hemoglobin, CAD coronary artery disease, SBP systolic blood pressure, DBP diastolic blood pressure, RHR resting heart rate, LM left main coronary artery, LAD left anterior descending artery, LCX left circumflex artery, RCA right coronary artery, FBG fasting blood glucose, LDL-C low-density lipoprotein cholesterol, HDL-C high-density lipoprotein cholesterol, TG triglycerides, TC total cholesterol, UA uric acid, Lp(a) lipoprotein (a), ApoA1 apolipoprotein A1, ApoB apolipoprotein B, BUN blood urea nitrogen, LVEF left ventricular ejection fraction, AP alkaline phosphatase.
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