Table 6 The penalty points for the determination of ERD using the different proposed methods.

From: Multiple green spectroscopic methods for erdosteine determination in bulk and dosage form with extensive greenness evaluation

Analytical eco-scale

Method I

Method II

Method III

Method IV

Reagents/instruments

Penalty Points (PP)

   

Potassium permanganate

8

   

Ceric ammonium sulphate

 

1

1

 

Acriflavine

   

4

Sodium hydroxide

2

   

Sulphuric acid

 

2

2

 

Britton robinson buffer

   

4

Energy

    

UV Spectrophotometer

0

0

  

Spectrofluorimeter

  

0

0

Occupational hazard

0

0

0

0

Waste 10 mL

3

3

3

3

Total penalty points

13

6

6

11

Analytical eco-scale total score

87

94

94

89

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