Table 3 Evaluation of intra-day and inter-day precision for the determination of KET and OLO.
Drug (method) | Concentration taken (µg/mL) | Intra-day precision | Inter-day precision | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
Mean concentration found* (µg/mL) | SD | Mean %recovery | SD | %R.S.D | Mean concentration found* (µg/mL) | SD | Mean %recovery | SD | %R.S.D | ||
KET (direct at 323 nm) | 4.0 | 4.02 | 0.037 | 100.386 | 0.930 | 0.926 | 4.02 | 0.010 | 100.530 | 0.239 | 0.238 |
6.0 | 6.02 | 0.044 | 100.416 | 0.737 | 0.734 | 6.04 | 0.027 | 100.616 | 0.449 | 0.446 | |
6.0 | 6.04 | 0.055 | 100.649 | 0.923 | 0.917 | 6.04 | 0.020 | 100.664 | 0.325 | 0.323 | |
OLO (1DR) | 40.0 | 40.04 | 0.322 | 100.096 | 0.805 | 0.804 | 40.02 | 0.013 | 100.058 | 0.033 | 0.033 |
20.0 | 20.06 | 0.278 | 100.293 | 1.388 | 1.384 | 20.09 | 0.088 | 100.464 | 0.442 | 0.440 | |
10.0 | 9.90 | 0.083 | 98.985 | 0.834 | 0.842 | 10.01 | 0.090 | 100.063 | 0.905 | 0.904 | |
OLO (DWM) | 40.0 | 39.85 | 0.416 | 99.624 | 1.041 | 1.045 | 39.95 | 0.079 | 99.876 | 0.197 | 0.197 |
20.0 | 20.16 | 0.236 | 100.800 | 1.182 | 1.173 | 20.07 | 0.094 | 100.373 | 0.468 | 0.466 | |
10.0 | 10.01 | 0.064 | 100.141 | 0.639 | 0.638 | 10.04 | 0.031 | 100.352 | 0.305 | 0.304 | |
