Table 4 Determination of KET and OLO in Lab-prepared eye drop by the developed methods and the reported spectrophotometric method.

From: UV spectrophotometric methods for simultaneous determination of ketorolac tromethamine and olopatadine hydrochloride: Application of multiple standard addition for assay of ophthalmic solution

Drug (method)

Developed methods

Reported method 18

t-Test

F-test

Mean % recovery* ± SD

KET (direct at 323 nm)

99.63 ± 0.01

98.54 ± 0.01

1.07

1.14

OLO (1DR)

100.31 ± 0.01

100.40 ± 0.02

0.08

1.98

OLO (DWM)

100.90 ± 0.02

98.96 ± 0.02

1.27

1.85

  1. *n = 3, Theoretical values for t‐test (0.05) is 2.77 and for F‐test (0.05) is 19.
Back to article page