Table 1 Characteristics of patients with acute or chronic pancreatitis and controls.
Control | Pancreatitis | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Total | SD | SAP | RAP | CP with AP | CP without AP | ||||||||
N, % | 4,514,960 | 100 | 451,496 | 100 | 215,765 | 47.8 | 10,046 | 2.2 | 43,350 | 0.9 | 182,335 | 40.4 | |
Sex | |||||||||||||
Male | 2,532,180 | 56.1 | 253,218 | 56.1 | 0.0 | 118,559 | 54.9 | 6299 | 62.7 | 28,894 | 66.7 | 99,466 | 54.6 |
Female | 1,982,780 | 43.9 | 198,278 | 43.9 | 97,206 | 45.1 | 3747 | 37.3 | 14,456 | 33.3 | 82,869 | 45.4 | |
Ages | |||||||||||||
Mean, SD | 56.8 | 14.6 | 56.8 | 14.6 | 57.5 | 15.0 | 57.9 | 14.4 | 57.3 | 13.1 | 55.8 | 14.1 | |
Hepatic fibrosis/cirrhosis | |||||||||||||
No | 4,416,857 | 97.8 | 417,118 | 92.4 | 0.3 | 200,720 | 93.0 | 8774 | 87.3 | 38,217 | 88.2 | 169,407 | 92.9 |
Yes | 98,103 | 2.1 | 34,378 | 7.6 | 15,045 | 7.0 | 1272 | 12.7 | 5133 | 11.8 | 12,928 | 7.1 | |
Alcoholic liver disease | |||||||||||||
No | 4,133,035 | 91.5 | 367,254 | 81.3 | 0.3 | 179,211 | 83.1 | 6814 | 67.8 | 29,646 | 68.4 | 151,583 | 83.1 |
Yes | 381,925 | 8.4 | 84,242 | 18.7 | 36,554 | 16.9 | 3232 | 32.2 | 13,704 | 31.6 | 30,752 | 16.9 | |
Gallstones | |||||||||||||
No | 4,314,229 | 95.6 | 373,304 | 82.7 | 0.4 | 173,648 | 80.5 | 7800 | 77.6 | 33,434 | 77.1 | 158,422 | 86.9 |
Yes | 200,731 | 4.4 | 78,192 | 17.4 | 42,117 | 19.5 | 2246 | 22.3 | 9916 | 22.9 | 23,913 | 13.2 | |
ALT (U/L) | |||||||||||||
< 40 | 4,030,496 | 89.3 | 384,172 | 85.1 | 0.1 | 184,261 | 85.4 | 8029 | 79.9 | 34,548 | 79.7 | 157,334 | 86.3 |
≥ 41 | 482,194 | 10.7 | 67,062 | 14.9 | 31,364 | 14.5 | 2009 | 20.0 | 8779 | 20.3 | 24,910 | 13.7 | |
Missing | 2270 | 0.1 | 262 | 0.1 | 140.0 | 0.1 | 8.0 | 0.1 | 23.0 | 0.1 | 91.0 | 0.0 | |
GGT (U/L) | |||||||||||||
< 76 | 3,814,110 | 84.5 | 344,296 | 76.3 | 0.2 | 165,122 | 76.5 | 6495 | 64.7 | 28,184 | 65.0 | 144,495 | 79.2 |
≥ 76 | 699,254 | 15.5 | 106,998 | 23.7 | 50,530 | 23.4 | 3547 | 35.3 | 15,147 | 34.9 | 37,774 | 20.7 | |
Missing | 1596 | 0.0 | 202 | 0.0 | 113 | 0.1 | 4 | 0.0 | 19 | 0.0 | 66 | 0.0 | |
BMI (Kg/m2) | |||||||||||||
< 18.5 | 145,080 | 3.2 | 18,363 | 4.1 | 0.1 | 8519 | 3.9 | 400 | 4.0 | 1892 | 4.4 | 7552 | 4.1 |
18.5–24.9 | 2,804,428 | 62.1 | 276,791 | 61.3 | 129,380 | 60.0 | 5978 | 59.5 | 26,594 | 61.3 | 114,839 | 63.0 | |
25.0–29.9 | 1,404,842 | 31.1 | 137,497 | 30.5 | 67,836 | 31.4 | 3173 | 31.6 | 13,133 | 30.3 | 53,355 | 29.3 | |
≥ 30 | 160,610 | 3.6 | 18,845 | 4.2 | 10,030 | 4.6 | 495 | 4.9 | 1731 | 4.0 | 6589 | 3.6 | |
FPG (mg/dL) | |||||||||||||
< 110 | 3,657,263 | 81.0 | 349,586 | 77.4 | 0.1 | 166,752.0 | 77.3 | 7454 | 74.2 | 32,142 | 74.1 | 143,238 | 78.6 |
110–125 | 471,938 | 10.5 | 51,795 | 11.5 | 24,900.0 | 11.5 | 1291 | 12.9 | 5672 | 13.1 | 19,932 | 10.9 | |
≥ 126 | 384,181 | 8.5 | 49,923 | 11.1 | 24,003.0 | 11.1 | 1297 | 12.9 | 5519 | 12.7 | 19,104 | 10.5 | |
Missing | 1578 | 0.0 | 192 | 0.0 | 110.0 | 0.1 | 4 | 0.0 | 17 | 0.0 | 61 | 0.0 | |
Cholesterol (mg/dL) | |||||||||||||
< 200 | 2,564,256 | 56.8 | 264,911 | 58.7 | 0.0 | 125,994 | 58.4 | 5735 | 57.1 | 25,192 | 58.1 | 107,990 | 59.2 |
200–239 | 1,401,953 | 31.1 | 132,225 | 29.3 | 63,425 | 29.4 | 2958 | 29.4 | 12,633 | 29.1 | 53,209 | 29.2 | |
≥ 240 | 546,524 | 12.1 | 54,110 | 12.0 | 26,215 | 12.1 | 1345 | 13.4 | 5503 | 12.7 | 21,047 | 11.5 | |
Missing | 2227 | 0.0 | 250 | 0.1 | 131 | 0.1 | 8 | 0.1 | 22 | 0.1 | 89 | 0.0 | |
Smoking (pack-year) | |||||||||||||
None | 2,896,207 | 64.1 | 277,035 | 61.4 | 0.1 | 133,110 | 61.7 | 5669 | 56.4 | 22,837 | 52.7 | 115,419 | 63.3 |
< 10 | 423,478 | 9.4 | 41,982 | 9.3 | 20,679 | 9.6 | 885 | 8.8 | 3927 | 9.1 | 16,491 | 9.0 | |
11–20 | 476,184 | 10.5 | 49,221 | 10.9 | 23,320 | 10.8 | 1281 | 12.8 | 5944 | 13.7 | 18,676 | 10.2 | |
21–30 | 311,992 | 6.9 | 34,852 | 7.7 | 16,303 | 7.6 | 943 | 9.4 | 4456 | 10.3 | 13,150 | 7.2 | |
31–40 | 176,425 | 3.9 | 20,648 | 4.6 | 9597 | 4.4 | 530 | 5.3 | 2685 | 6.2 | 7836 | 4.3 | |
≥ 40 | 176,142 | 3.9 | 21,923 | 4.9 | 10,209 | 4.7 | 573 | 5.7 | 2825 | 6.5 | 8316 | 4.6 | |
Missing | 54,532 | 1.2 | 5835 | 1.3 | 2547 | 1.2 | 165 | 1.6 | 676 | 1.6 | 2447 | 1.3 | |
Alcohol (drinks/week) | |||||||||||||
None | 2,300,662 | 51.0 | 225,940 | 50.0 | 0.1 | 112,014 | 51.9 | 4511 | 44.9 | 18,416 | 42.5 | 90,999 | 49.9 |
< One/month | 981,054 | 21.7 | 89,814 | 19.9 | 43,476 | 20.1 | 1688 | 16.8 | 7813 | 18.0 | 36,837 | 20.2 | |
< One/week | 288,408 | 6.4 | 27,642 | 6.1 | 11,311 | 5.2 | 832 | 8.3 | 3436 | 7.9 | 12,063 | 6.6 | |
≥ One/week | 622,561 | 13.8 | 76,975 | 17.0 | 35,710 | 16.6 | 2202 | 21.9 | 10,454 | 24.1 | 28,609 | 15.7 | |
Missing | 322,275 | 7.1 | 31,125 | 6.9 | 13,254 | 6.1 | 813 | 8.1 | 3231 | 7.5 | 13,827 | 7.6 | |
Physical activity | |||||||||||||
None | 2,330,298 | 51.6 | 240,277 | 53.2 | 0.0 | 118,223 | 54.8 | 5625 | 56.0 | 23,189 | 53.5 | 93,240 | 51.1 |
Light-moderate | 1,204,603 | 26.7 | 116,288 | 25.8 | 53,948 | 25.0 | 2313 | 23.0 | 10,985 | 25.3 | 49,042 | 26.9 | |
Vigorous | 923,023 | 20.4 | 89,138 | 19.7 | 41,146 | 19.1 | 1935 | 19.3 | 8553 | 19.7 | 37,504 | 20.6 | |
Missing | 57,036 | 1.3 | 5793 | 1.3 | 2448 | 1.1 | 173 | 1.7 | 623 | 1.4 | 2549 | 1.4 | |
