Table 1 Relationship of IL-8 and CD97 expression with clinicopathological factors.
Factor | Number | IL-8 expression (n,%) | P | CD97 expression (n,%) | P | ||
|---|---|---|---|---|---|---|---|
Low | High | Low | High | ||||
Sex | |||||||
Female | 61 | 17(27.9) | 44(72.1) | 0.448 | 17(27.9) | 44(72.1) | 0.840 |
Male | 64 | 22(34.4) | 42(65.6) | 16(25.0) | 48(75.0) | ||
Age at diagnosis (years) | 125 | 57.56 ± 10.19a | 58.45 ± 10.71a | 0.663 | 58.39 ± 10.51a | 58.10 ± 10.58a | 0.890 |
Histological differentiation | |||||||
Well | 11 | 8(72.7) | 3(27.3) | 0.001* | 7(63.6) | 4(36.4) | 0.007* |
Moderately | 78 | 27(34.6) | 51(65.4) | 21(26.9) | 57(73.1) | ||
Poorly | 36 | 4(11.1) | 32(88.9) | 5(13.9) | 31(86.1) | ||
Lymph node metastasis | |||||||
Negative | 81 | 31(38.3) | 50(61.7) | 0.026* | 30(37.0) | 51(63.0) | 0.001* |
Positive | 44 | 8(18.2) | 36(81.8) | 3(6.8) | 41(93.2) | ||
Vascular invasion | |||||||
Negative | 91 | 36(39.6) | 55(60.4) | 0.001* | 32(35.2) | 59(64.8) | 0.001* |
Positive | 34 | 3(8.8) | 31(91.2) | 1(2.9) | 33(97.1) | ||
Nerve invasion | |||||||
Negative | 79 | 27(34.2) | 52(65.8) | 0.425 | 19(24.1) | 60(75.9) | 0.529 |
Positive | 46 | 12(26.1) | 34(73.9) | 14(30.4) | 32(69.6) | ||
Tumor size | |||||||
< 3 cm | 44 | 15(34.1) | 29(65.9) | 0.687 | 14(31.8) | 30(68.2) | 0.396 |
> 3 cm | 81 | 24(29.6) | 57(70.4) | 19(23.5) | 62(76.5) | ||
Tumor nodules | |||||||
Single | 100 | 32(32.0) | 68(68.0) | 0.812 | 27(27.0) | 73(73.0) | 1.000 |
Multiple | 25 | 7(28.0) | 18(72.0) | 6(24.0) | 19(76.0) | ||
CD97 expression | |||||||
Low | 33 | 24(72.7) | 9(27.3) | 0.001* | |||
High | 92 | 15(16.3) | 77(83.7) | ||||