Table 2 Univariate and multivariate analyses for the relevance of prognosis with various clinicopathological factors.

From: IL-8 is a novel prometastatic chemokine in intrahepatic cholangiocarcinoma that induces CXCR2-PI3K/AKT signaling upon CD97 activation

Factor

Univariate analysis P

Multivariate analysis (Cox)

P

Hazard ratio (HR)

95% confidence interval (CI)

Sex

0.133

   

Age at diagnosis

0.697

   

Histological differentiation

0.001*

   

Lymph node metastasis

0.001*

1.851

1.137–3.014

0.013*

Vascular invasion

0.001*

   

Nerve invasion

0.662

   

Tumor size

0.501

   

Tumor nodules

0.627

   

IL-8 expression

0.001*

4.585

2.312–9.091

0.001*

CD97 expression

0.001*

2.662

1.314–5.393

0.007*

  1. *P < 0.05.
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