Table 3 Assessing directional pleiotropy through MR-Egger intercept.

From: Deciphering genetic causality between inflammatory bowel disease and periodontitis through bi-directional two-sample Mendelian randomization

Outcome

Exposure

Intercept

SE

P

Periodontitis

IBD

0.003

0.003

0.439

Periodontitis

CD

0.002

0.004

0.553

Periodontitis

UC

0.005

0.006

0.428

IBD

Periodontitis

− 0.016

0.013

0.298

CD

Periodontitis

− 0.024

0.018

0.250

UC

Periodontitis

− 0.013

0.017

0.478

  1. IBD inflammatory bowel disease, CD Crohn's disease, UC ulcerative colitis, MR Mendelian randomization, SE standard error, P: P value tests the null hypothesis of no association with exposure.