Table 2 Univariate and multivariate Cox regression analysis of clinicopathological characteristics associated with disease-free survival in patients with colorectal cancer.
Clinicopathological characteristics | Disease-free survival | |||
|---|---|---|---|---|
Univariate analysis | Multivariate analysis | |||
HR (95%CI) | P value | HR (95%CI) | P value | |
Age | 1.356 (1.135–1.619) | 0.001 | 1.508 (1.256—1.810) | < 0.001 |
T stage (T3–4) | 2.034 (1.617–2.558) | < 0.001 | 1.481 (1.159—1.892) | 0.002 |
N stage | ||||
N0 | Ref | |||
N1 | 1.798 (1.460–2.214) | < 0.001 | 1.586 (1.280—1.967) | < 0.001 |
N2 | 4.048 (3.250–5.042) | < 0.001 | 3.262 (2.568—4.143) | < 0.001 |
Perineural invasion (Positive) | 1.678 (1.292–2.179) | < 0.001 | 0.993 (0.742—1.328) | 0.960 |
Vascular invasion (Positive) | 1.995 (1.619–2.457) | < 0.001 | 1.426 (1.124—1.809) | 0.003 |
Macroscopic type | ||||
Protrude type | Ref | |||
Infiltrating type | 1.539 (1.091–2.170) | 0.014 | 1.447 (1.024—2.045) | 0.036 |
Ulcerative type | 1.387 (1.119–1.719) | 0.003 | 1.153 (0.925—1.437) | 0.205 |
Differentiation (High-medium) | 0.699 (0.548–0.893) | 0.004 | 0.865 (0.673—1.112) | 0.256 |
Tumor location (Colon cancer) | 0.800 (0.670–0.956) | 0.014 | 0.783 (0.653—0.939) | 0.008 |
CIPI (High) | 1.694 (1.420–2.021) | < 0.001 | 1.443 (1.203—1.730) | < 0.001 |
