Table 3 Results of CHO-K1/HPRT mutation assay without activation expressed as average values of three replicates (plates) ± sample standard deviations.

From: Toxicological investigation of lilial

Sample

NMC

PE (%)

MF (/106)

NC

0 ± 0

95 ± 11

0 ± 0

VC

1 ± 1

103 ± 3

3 ± 3

PC: EMS

10 ± 3

108 ± 13

48 ± 12***

Lilial 50 µM

2 ± 1

117 ± 1

9 ± 4

  1. VC vehicle control, NC negative control, PC positive control, NMC number of mutant colonies, PE plating efficiency, MF mutation frequency, EMS ethylmethanesulfonate. Statistical significance was verified by ANOVA followed by Tukey test (*p ˂ 0.05, **p ˂ 0.01, ***p˂ 0.001).