Table 2 Effectiveness of the therapy.

Centers

 Clinical staff professionals over the median: No versus Yes

1.00 (0.90–1.12)

0.9628

 Hours/year/patient of work over the median: No versus Yes

1.13 (0.63–2.03)

0.6824

 Median time from the request to diagnosis (months)

1.00 (1.00–1.00)

0.0002*

Patients

 Age at diagnosis

0.98 (0.96–1.01)

0.1501

 Sex: Male versus Female

0.88 (0.74–1.05)

0.1539

 Only child: Yes versus No

1.09 (0.95–1.24)

0.2155

 Born abroad: Yes versus No

0.53 (0.39–0.71)

 < 0.0001*

 Adopted child: Yes versus No

0.66 (0.47–0.93)

0.0173*

 School failures: Yes versus No

0.66 (0.48–0.90)

0.0083*

 Employed parents: Yes versus No

0.79 (0.70–0.90)

0.0002*

 Family history of ADHD: Yes versus No

1.09 (0.94–1.28)

0.2500

 Dystocic delivery: Yes versus No

0.97 (0.84–1.12)

0.6829

 Preterm/low weight: Yes versus No

0.81 (0.68–0.98)

0.0261*

 Exclusive breastfeeding (≥ 3 months): Yes versus No

1.13 (0.99–1.28)

0.0658

 Motor delay: Yes versus No

2.45 (1.84–3.28)

 < 0.0001*

 Language delay Yes versus No

0.54 (0.47–0.62)

 < 0.0001*

 ADHD type H/I versus C

1.05 (0.93–1.20)

0.4158

 CGI-S score at diagnosis 5–7 versus 3–4

0.95 (0.82–1.09)0.95 (0.83–1.10)

0.5116

Comorbidities

 Psychiatric comorbidities: Yes versus No

1.04 (0.87–1.24)

0.6619

 Chronic diseases: Yes versus No

0.90 (0.69–1.17)

0.4356

Therapy versus None

 Combined

4.61 (3.87–5.49)

 < 0.0001*

 Methylphenidate alone

2.70 (2.27–3.21)

 < 0.0001*

 Psychological alone

2.05 (1.75–2.41)

 < 0.0001*