Table 1 The imaging performance of Morphologi 4-ID depending on size of particles. The processed images were captured in each measurement and compared with the original particles of interest shown under microscope.

From: Morphologically-Directed Raman Spectroscopy as an Analytical Method for Subvisible Particle Characterization in Therapeutic Protein Product Quality

Particle size (μm)

High quality image (%)

≥ 19 μm

> 90

18–19

78.6

17–18

76.9

16–17

70.0

Particle ID

Diameter (μm)

Particle of interest

Processed image

Particle ID

Diameter (μm)

Particle of interest

Processed image

1689

56.6

3399

17.4

636

34.4

1176

16.1

2523

25.1

1958

15.3

3031

20.1

2208

14.5

3298

18.2

1647

13.1