Figure 4 | Scientific Reports

Figure 4

From: Orange juice containing Pediococcus acidilactici CE51 modulates the intestinal microbiota and reduces induced inflammation in a murine model of colitis

Figure 4

Reduction of C-reactive protein levels after 15 days of treatment with P. acidilactici CE51 on DSS-induced colitis. Serum concentrations of TNF-α (A) and C-reactive protein (B) from mice treated for 5 days (n = 4) and 15 days (n = 5) with probiotic (orange juice containing Pediococcus acidilactici CE51), placebo (orange juice) and sulfasalazine (10 mg/kg/weight) after DSS administration (3%) to induce colitis. The concentration of TNF-α and C-reactive protein (CRP) were determined by the enzyme-linked immunosorbent assay (ELISA) and, in the final of the test, the resulting absorbance was measured spectrophotometrically at 450 nm. The control group was not submitted to the colitis protocol. *Statistical difference in relation to the control group (p < 0.05). aStatistical difference in relation to the colitis, placebo and probiotic group (p < 0.05).

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