Table 3 Associations between immune cell subtype cluster and breast cancer survival.

From: Machine learning-based cluster analysis of immune cell subtypes and breast cancer survival

Dataset

Relapse-free survival

Overall survival

Relapse-free survival*

Overall survival*

HR

95%CI

P

HR

95%CI

P

HR

95%CI

P

HR

95%CI

P

METABRIC

  

0.001

  

< 0.001

  

0.009

  

0.011

 Cluster A

1

  

1

  

1

  

1

  

 Cluster B

1.42

1.15–1.74

 

1.60

1.28–2.00

 

1.38

1.08–1.76

 

1.37

1.08–1.75

 

Turin study

  

0.028

  

0.114

  

0.154

  

0.358

 Cluster A

1

  

1

  

1

  

1

  

 Cluster B

1.87

1.07–3.27

 

1.74

0.85–3.47

 

1.53

0.85–2.73

 

1.40

0.68–2.89

 

TCGA#

  

0.072

  

0.017

  

0.002

  

0.004

 Cluster A

1

  

1

  

1

  

1

  

 Cluster B

1.54

0.96–2.47

 

1.63

1.09–2.43

 

2.24

1.34–3.74

 

1.93

1.24–3.01

 
  1. *Adjusted for age, stage, grade, ER, PR, and histology.
  2. #Tumor grade not included in multivariate analysis.
  3. Significant values are in bold.
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