Table 2 Results of mental health (GHQ-28) in the studied patients (Case n = 20, Control n = 20).

From: The effect of probiotic supplementation on the clinical and para-clinical findings of multiple sclerosis: a randomized clinical trial

Variable

Probiotic group

N = 20

Placebo group

N = 20

p**

p***

GHQ somatic, (points)

 Before intervention,

14.85 ± 4.19

14.55 ± 2.83

0.793

 < 0.001

 After intervention

16.65 ± 2.75

14.65 ± 2.36

0.021

 Mean changes*

1.80 ± 1.90

0.10 ± 1.25

0.004

GHQ anxiety/insomnia, (points)

 Before intervention

16.15 ± 3.88

15.75 ± 3.22

0.725

0.719

 After intervention

17.15 ± 2.96

16.70 ± 2.59

0.612

 Mean changes*

1.00 ± 2.99

0.95 ± 2.13

0.968

GHQ social dysfunction, (points)

 Before intervention

14.20 ± 4.34

14.55 ± 4.04

0.743

0.041

 After intervention

15.80 ± 2.54

15.01 ± 3.30

0.967

 Mean changes*

1.60 ± 2.77

0.46 ± 2.29

0.011

GHQ depression, (points)

 Before intervention

18.75 ± 3.07

19.90 ± 1.48

0.497

0.508

 After intervention

19.50 ± 1.79

19.55 ± 1.50

0.812

 Mean changes*

0.75 ± 2.42

− 0.35 ± 1.92

0.327

  1. All values are presented as mean ± SD.
  2. *Paired-samples t-test (statistically significant values are shown in bold).
  3. **One-way ANOVA.
  4. ***Analysis of covariance (ANCOVA) adjusted for baseline measures.