Figure 1
Comparison of plasma inhibitory efficacy against B1.1.529 (Omicron) and Wuhan Hu-1 following different vaccination strategies. Serum samples of participants with 4 doses (n = 40) or 5 doses (n = 16) were collected to evaluate % inhibition against B1.1.529 (Omicron) and Wuhan Hu-1 SARS-CoV-2. (A) Shows a flow of participants through the study. In (B–D) data represent individual participant measurements (open purple circle for 4 doses, open green circle for 5 doses) with the horizontal lines showing median and 95% confidence interval (95% CI) and dash line represents a positive cut-off. (B) Shows differences in % inhibition of different viral strains and different vaccinations regimens with responses against Omicron (open purple circle, open green circle) and against Wuhan Hu-1 (open purple triangle, open green triangle). (C,D) Show % inhibition of B1.1.529 (Omicron) with different vaccination strategies after 4 doses or 5 doses, respectively. Data were analysed using Kruskal–Wallis test with Dunn’s multiple comparisons test. Statistical significance was determined at a p-value < 0.05.
