Table 2 Cox regression univariate analysis: predictors of severe atlantoaxial joint involvement in our cohort in retrospective phase of the study.

From: The assessment of atlantoaxial joint involvement in patients with rheumatoid arthritis, results from an observational “real-life” study

Clinical variables

HR

95% CI

p-values

Age

0.98

0.95–1.02

0.020

Male gender

10.97

2.48–48.81

0.002

Smoking habit

1.36

0.83–10.93

0.566

ACPA

4.87

1.10–21.60

0.037

RF

3.92

0.85–17.40

0.072

Disease duration

1.06

1.01–1.10

0.022

Extra-articular disease

7.83

2.81–21.81

< 0.001

Surgery

2.80

0.66–6.61

0.580

MTX

0.52

0.30–2.27

0.500

TNFi

2.28

0.81–6.38

0.900

Non-TNFi

0.95

0.25–3.21

0.903

  1. ACPA anticitrullinated protein antibodies, RF rheumatoid factor, MTX methotrexate, TNFis tumor necrosis factor.
  2. Significant values are in bold.